Global Conference on Medical and Health Sciences
type: channel
description: Global Conference on Medical and Health Sciences Aim & Scope: This conference focuses on medical research, clinical studies, public health, healthcare systems, and biomedical sciences. It promotes evidence-based research addressing regional and global health challenges. About E-Conferencia Platform: E-Conferencia ensures ethical handling of medical research publications, providing open access to conference outputs while following responsible academic publishing practices. Hosted Online from: Madrid, Spain Schedule: 14th of Each Month
publisher: E-Conferencia
language: en
publication name: Global Conference on Medical and Health Sciences
items: GAZNI SINTETIK YOQILG’IGA AYLANTIRISH (Gas-To-Liquids)
items: HEALTH-RELATED QUALITY OF LIFE AFTER KIDNEY TRANSPLANTATION: CURRENT EVIDENCE AND CLINICAL IMPLICATIONS
items: STRUCTURAL INVOLUTION AND REMODELING OF LYMPH NODES IN RHEUMATOID ARTHRITIS
items: ГЕМОДИАЛИЗ ЎТКАЗИЛАЁТГАН БЕМОРЛАРДА ФИБРОБЛАСТ-23 НИНГ АҲАМИЯТИ
items: БУЙРАК КЎЧИРИБ ЎТКАЗИЛГАН БЕМОРЛАРДА ЛАБОРАТОР КЎРСАТГИЧЛАР ВА УЛАР ОРАСИДАГИ КОРРЕЛЯЦИОН БОҒЛИҚЛИКЛАРНИ БАҲОЛАШ
items: ГЕМОДИАЛИЗ ЎТКАЗИЛАЁТГАН МУОЛАЖАЛАРНИНГ ТУРЛИ МУДДАТЛАРИДА БЕМОРЛАРДА ЛАБОРАТОР КЎРСАТГИЧЛАР ВА УЛАР ОРАСИДАГИ КОРРЕЛЯЦИОН БОҒЛИҚЛИКЛАРНИ БАҲОЛАШ
items: TURISTIK MAHSULOTLAR DIVERSIFIKATSIYASI VA SOHAGA INVESTITSIYALARNI JALB ETISH MEXANIZMLARI: GLOBAL TENDENSIYALAR VA MILLIY AMALIYOT
items: ISSUES OF TAKING INTO ACCOUNT THE PSYCHOLOGICAL-PEDAGOGICAL CHARACTERISTICS OF STUDENTS IN TEACHING ENGLISH PHONETICS
items: https://econferencia.com/index.php/5/article/view/355
items: ENDOVASCULAR TREATMENT OF TANDEM CAROTID ARTERY STENOSES IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS
items: ENDOVASCULAR INTERVENTIONS IN CAROTID ARTERIES IN PATIENTS WITH CORONARY ARTERY DISEASE
items: DIGITAL TRANSFORMATION IN HIGHER EDUCATION: STUDENT ENGAGEMENT AND THE EFFECTIVENESS OF DIGITAL LEARNING RESOURCES
items: ARSMEDICA: AN ARTIFICIAL INTELLIGENCE–DRIVEN PLATFORM FOR SCHOLARLY DATABASE NAVIGATION AND SCIENTIFIC PUBLISHING SUPPORT
items: BODY MASS INDEX–ASSOCIATED PATTERNS OF REPRODUCTIVE DYSFUNCTION IN PUBERTAL GIRLS
items: NANOBIOPHYSICAL CHARACTERIZATION OF TARGETED DRUG DELIVERY SYSTEMS FOR ENHANCED CANCER THERAPY EFFICIENCY
items: THE INFLUENCE OF LIFESTYLE AND METABOLIC SYNDROME ON BREAST CANCER INCIDENCE AND PROGNOSIS
items: THE ROLE OF GENETIC SCREENING AND BRCA TESTING IN EARLY IDENTIFICATION OF HIGH-RISK BREAST CANCER PATIENTS
items: PEDAGOGICAL CONDITIONS FOR DEVELOPING STUDENTS’ COMPARATIVE THINKING THROUGH FABLES
items: CLINICAL AND PATHOPHYSIOLOGICAL FEATURES OF THE DEVELOPMENT OF ISCHEMIC HEART DISEASE IN PATIENTS WITH DIABETES MELLITUS
items: TUMOR-RELATED CEREBRAL EDEMA: MECHANISMS AND IMAGING FEATURES
items: TALABALARDA SUN’IY INTELLEKT ASOSIDA OGʻZAKI NUTQNI RIVOJLANTIRISHNING MASHQLAR TIZIMI
items: ЭМБРИОН РИВОЖЛАНИШДАГИ КЕЛИБ ЧИҚАДИГАН НУҚСОНЛАР
items: STUDYING THE TENDENCY OF PATIENTS WITH CHRONIC HEART-VASCULAR AND RESPIRATORY DISEASES LIVING IN THE VILLAGE TO BE TREATED
items: PRACTICE OF ATTRACTING GRANTS, FUNDS AND INTERNATIONAL FINANCIAL RESOURCES IN HIGHER EDUCATION
items: DIGITALIZING HIGHER EDUCATION HEMIS INFORMATION SYSTEM
items: METHODOLOGY OF USING VISUAL TOOLS IN TEACHING GEOMETRY TOPICS
items: EARLY DIAGNOSIS AND PROGNOSTIC OPTIMIZATION OF ACUTE KIDNEY INJURY IN THE INTENSIVE CARE SETTING
items: BIOLOGICAL DIVERSITY IN THE HYDROSPHERE SHELL AND ITS SIGNIFICANCE IN NATURE
items: ЛОГИСТИКА ХИЗМАТЛАРИДА СТРАТЕГИК РЕЖАЛАШТИРИШНИНГ МОҲИЯТИ ВА АҲАМИЯТИ
items: САВДО ХИЗМАТЛАРИ ТИЗИМИДА МАҲСУЛОТЛАР СИФАТИНИ РИВОЖЛАНТИРИШ ЙЎЛЛАРИ

GAZNI SINTETIK YOQILG’IGA AYLANTIRISH (Gas-To-Liquids)
type: item
description: Neftning tarkibidagi yo‘ldosh gazlardan tejamkorlik bilan foydalanish asosida yangi mahsulotlarni ishlab chiqarish har bir neft kompaniyasining asosiy maqsadlaridan biri hisoblanadi.
subject: Articles
  topic: section
creator: Suyarov M. T.
creator: Husenov SH. B.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-04-03
publication date: 2026-04-03
starting page: 167
ending page: 170

HEALTH-RELATED QUALITY OF LIFE AFTER KIDNEY TRANSPLANTATION: CURRENT EVIDENCE AND CLINICAL IMPLICATIONS
type: item
description: Background:Kidney transplantation is the preferred treatment for end-stage renal disease, offering survival benefits over dialysis. However, long-term outcomes increasingly focus on health-related quality of life (HRQoL). Objective: To analyze contemporary evidence on HRQoL after kidney transplantation and identify key determinants affecting patient outcomes. Methods: Narrative review of recent studies (2020–2026) addressing HRQoL, psychological status, and clinical determinants in kidney transplant recipients. Results: Kidney transplantation significantly improves HRQoL compared to dialysis, particularly in physical and social domains. However, HRQoL remains lower than in the general population. Immunosuppressive therapy, psychological disorders, and comorbidities are major limiting factors. Conclusion: HRQoL should be considered a core outcome in transplant medicine, requiring multidisciplinary management and individualized therapeutic strategies.
subject: Articles
  topic: section
subject: Kidney transplantation, quality of life, HRQoL, immunosuppression, renal failure
  topic: keywords
creator: Qoriyev M. S.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-04-03
publication date: 2026-04-03
starting page: 161
ending page: 166

STRUCTURAL INVOLUTION AND REMODELING OF LYMPH NODES IN RHEUMATOID ARTHRITIS
type: item
description: The aim of the study was to morphometrically assess age-related morphofunctional changes in lymph nodes, including structural remodeling associated with increased stromal components and medullary zone reduction, in 18-month-old albino rats under chronic rheumatoid arthritis conditions, and to compare the findings with a control group.
subject: Articles
  topic: section
creator: Avezov B. B.
creator: Sadiyev E. S.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-31
publication date: 2026-03-31
starting page: 158
ending page: 160

ГЕМОДИАЛИЗ ЎТКАЗИЛАЁТГАН БЕМОРЛАРДА ФИБРОБЛАСТ-23 НИНГ АҲАМИЯТИ
type: item
description: Илмий изланишда гемодиализ олаётган беморларда фибробласт-23 ўрганилган ва унинг фосфор, кальций, витамин D ва паратгормон билан ўзаро кучли боғлиқлиги ҳамда уни организмда фосфат гoмeостазида марказий роль ўйнаши кўрсатилган. Ушбу натижа гемодиализ илк марта бошланган беморларда олинган кучли корреляцион алоқалар билан тасдиқлаган. Узоқ вақт давомида гемодиализ олган беморларда боғлиқликларнинг камайиши организмнинг мослашиши ва ўтказилган даво муолажалари билан боғлиқлиги аниқланган.
subject: Articles
  topic: section
subject: гемодиализ, сурункали буйрак касаллиги, фибробласт-23, паратгармон, витамин-Д
  topic: keywords
creator: Махманов Лутфулло Сайдуллаевич
creator: Гадаев Абдигаффор Гадаевич
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-27
publication date: 2026-03-27
starting page: 144
ending page: 157

БУЙРАК КЎЧИРИБ ЎТКАЗИЛГАН БЕМОРЛАРДА ЛАБОРАТОР КЎРСАТГИЧЛАР ВА УЛАР ОРАСИДАГИ КОРРЕЛЯЦИОН БОҒЛИҚЛИКЛАРНИ БАҲОЛАШ
type: item
description: Мақолада буйрак трансплантацияси ўтказилган беморларда лаборатор кўрсатгичлари динамикада солиштирма ўрганилган. Шунингдек, уларда фибробласт-23 нинг фосфор, кальций, витамин D ва паратгормон билан ўзаро боғлиқлиги ҳамда организмда фосфат гomeостазида марказий роль ўйнаши кўрсатилган. Ушбу натижа буйрак трансплантацияси ўтказилган беморларда қайд этилган кучли корреляцион боғлиқликлар ёрдамида тасдиқлаган.
subject: Articles
  topic: section
subject: сурункали буйрак касаллиги, фибробласт-23, паратгармон, витамин-Д.
  topic: keywords
creator: Махманов Лутфулло Сайдуллаевич
creator: Гадаев Абдигаффор Гадаевич
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-27
publication date: 2026-03-27
starting page: 126
ending page: 143

ГЕМОДИАЛИЗ ЎТКАЗИЛАЁТГАН МУОЛАЖАЛАРНИНГ ТУРЛИ МУДДАТЛАРИДА БЕМОРЛАРДА ЛАБОРАТОР КЎРСАТГИЧЛАР ВА УЛАР ОРАСИДАГИ КОРРЕЛЯЦИОН БОҒЛИҚЛИКЛАРНИ БАҲОЛАШ
type: item
description: Ушбу илмий ишда гемодиализ олаётган беморларда лаборатор кўрсатгичлар динамикада солиштирма ўрганилган. Шунингдек, фибробласт-23 нинг фосфор, кальций, витамин D ва паратгормон билан ўзаро кучли боғлиқлиги ҳамда уни организмда фосфат гoмeостазида марказий роль ўйнаши кўрсатилган. Ушбу натижа гемодиализ илк марта бошланган беморларда олинган кучли корреляцион алоқалар билан тасдиқлаган. Узоқ вақт давомида гемодиализ олган беморларда боғлиқликларнинг камайиши организмнинг мослашиши ва ўтказилган даво муолажалари билан боғлиқлиги аниқланган.
subject: Articles
  topic: section
subject: гемодиализ, сурункали буйрак касаллиги, фибробласт-23, паратгармон, витамин-Д
  topic: keywords
creator: Махманов Лутфулло Сайдуллаевич
creator: Гадаев Абдигаффор Гадаевич
creator: Абдухолиқов Ойбек Зиядулла ўғли
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-27
publication date: 2026-03-27
starting page: 109
ending page: 125

TURISTIK MAHSULOTLAR DIVERSIFIKATSIYASI VA SOHAGA INVESTITSIYALARNI JALB ETISH MEXANIZMLARI: GLOBAL TENDENSIYALAR VA MILLIY AMALIYOT
type: item
description: Ushbu maqolada global integratsiya sharoitida turizm bozorining transformatsiyasi, xususan, turistik mahsulotlarni diversifikatsiya qilish zarurati ilmiy jihatdan asoslab berilgan. Tadqiqotda investitsiya muammolarining innovatsion jarayonlar bilan uzviy bog‘liqligi, turizmning “katta ochiq tizim” sifatidagi xususiyatlari hamda mintaqaviy rivojlanishga ta’siri tahlil qilingan. Shuningdek, O‘zbekistonda yangi turizm turlarini rivojlantirish va sohaga investitsiya kiritishning samarali mexanizmlari, jumladan, klaster yondashuvi va davlat-xususiy sheriklik modellari bo‘yicha takliflar ishlab chiqilgan.
subject: Articles
  topic: section
subject: Diversifikatsiya, investitsion iqlim, turistik mahsulot, innovatsion investitsiya, mintaqaviy iqtisodiyot, turizm klasteri, barqaror rivojlanish, muqobil turizm.
  topic: keywords
creator: Ismoilov Bekzod Muxidinovich
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-27
publication date: 2026-03-27
starting page: 102
ending page: 108

ISSUES OF TAKING INTO ACCOUNT THE PSYCHOLOGICAL-PEDAGOGICAL CHARACTERISTICS OF STUDENTS IN TEACHING ENGLISH PHONETICS
type: item
description: This article discusses the issues of taking into account the psychological and pedagogical characteristics of students in the process of teaching English phonetics to students of higher educational institutions. It analyzes how age-specific cognitive, affective and individual differences of students affect the process of forming phonetic skills. Also, the role of auditory perception, articulatory program, zonal patterns and auditory control is substantiated on the basis of scientific sources. The author emphasizes the need to create a person-oriented, multimodal and stress-free learning environment in phonetic teaching.
subject: Articles
  topic: section
subject: phonetic competence, pronunciation, auditory perception, articulation, psychological factors, individual approach, multimodal education
  topic: keywords
creator: Khalimova Dilshoda Nurhakim qizi
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-25
publication date: 2026-03-25
starting page: 94
ending page: 101

https://econferencia.com/index.php/5/article/view/355
type: item
title: ВЛИЯНИЕ ДЕСЕНСИБИЛИЗАЦИИ И ИНДИВИДУАЛИЗИРОВАННОЙ ИММУНОСУПРЕССИВНОЙ ТЕРАПИИ НА ПРОФИЛАКТИКУ ОТТОРЖЕНИЯ ТРАНСПЛАНТАТА У ВЫСОКОСЕНСИБИЛИЗИРОВАННЫХ РЕЦИПИЕНТОВ С УЧЁТОМ МОРФОЛОГИЧЕСКИХ ХАРАКТЕРИСТИК ТРАНСПЛАНТАТА
description: Целью исследования явилась оценка клинической эффективности комплекса лечебных мероприятий, направленных на снижение риска отторжения у высокосенсибилизированных реципиентов почечного трансплантата, с учетом морфологических изменений трансплантата в раннем послеоперационном периоде. В исследование включены 31 высокосенсибилизированных пациента с уровнем PRA выше 70% и наличием дооперационных DSA, которым выполнена трансплантация почки от живого родственного донора. Всем пациентам была проведена предтрансплантационная десенсибилизация с применением внутривенного иммуноглобулина и ритуксимаба. Иммуносупрессия включала индукционную терапию базиликсимабом и последующее поддерживающее лечение такролимусом, микофенолатом и метилпреднизолоном.
subject: Articles
  topic: section
creator: Курбанов Обид Махсудович
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-23
publication date: 2026-03-23
starting page: 92
ending page: 93

ENDOVASCULAR TREATMENT OF TANDEM CAROTID ARTERY STENOSES IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS
type: item
description: Tandem stenoses of the brachiocephalic arteries represent a complex form of multifocal atherosclerosis and are associated with an increased risk of ischemic stroke. The aim of this study was to evaluate the safety and effectiveness of endovascular treatment of tandem carotid artery stenoses.
subject: Articles
  topic: section
subject: carotid artery stenosis; tandem lesions; endovascular treatment; carotid artery stenting; multifocal atherosclerosis; cerebral protection devices; ischemic stroke
  topic: keywords
creator: Sultonov M. A.1
creator: Asliyev U. M. 1
creator: Musurmonov A. N. 1
creator: Mardonov J. N.1,2
creator: Makhmudov K.O. 1,2
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-19
publication date: 2026-03-19
starting page: 87
ending page: 91

ENDOVASCULAR INTERVENTIONS IN CAROTID ARTERIES IN PATIENTS WITH CORONARY ARTERY DISEASE
type: item
description: Carotid artery stenosis is a major contributor to ischemic stroke and is commonly associated with coronary artery disease (CAD), particularly in the setting of multifocal atherosclerosis [1,2]. This study aimed to assess the safety and efficacy of carotid artery stenting (CAS) in patients with symptomatic and asymptomatic carotid stenosis and concomitant CAD. A total of 55 patients treated between 2021 and 2024 were included. The mean age was 65.5 ± 4.5 years, and the degree of internal carotid artery stenosis ranged from 40% to 99%. Most patients had significant comorbidities, including arterial hypertension (76.3%), diabetes mellitus (41.8%), and a history of myocardial infarction (30.9%). All patients received dual antiplatelet therapy prior to intervention. A total of 57 CAS procedures were performed using self-expanding nitinol stents and embolic protection devices. The technical success rate was 100%, with effective restoration of vessel patency in all cases. Pre-dilatation was required in patients with critical stenosis. No major neurological complications, myocardial infarctions, or in-hospital mortality were observed. Transient neurological deficits occurred in 12.7% of patients, with complete recovery during hospitalization. Carotid artery stenting is a safe and effective minimally invasive method for stroke prevention in patients with CAD and carotid artery disease. It may serve as a viable alternative to surgical treatment, particularly in high-risk patients with multifocal atherosclerosis [3].
subject: Articles
  topic: section
subject: carotid artery stenosis; carotid artery stenting; coronary artery disease; multifocal atherosclerosis; endovascular treatment; embolic protection devices; ischemic stroke
  topic: keywords
creator: Sultonov M. A.
creator: Asliyev U. M.
creator: Musurmonov A. N.
creator: Mardonov J. N.
creator: Makhmudov K. O.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-19
publication date: 2026-03-19
starting page: 83
ending page: 86

DIGITAL TRANSFORMATION IN HIGHER EDUCATION: STUDENT ENGAGEMENT AND THE EFFECTIVENESS OF DIGITAL LEARNING RESOURCES
type: item
description: The rapid development of digital technologies has significantly transformed higher education systems worldwide. Universities increasingly integrate digital learning resources, online platforms, and virtual learning environments into their teaching practices. This transformation has accelerated particularly in recent years due to the expansion of online education and the growing demand for flexible learning opportunities. The purpose of this study is to analyze the role of digital learning resources in improving student engagement and learning outcomes in higher education. The research is based on a review of contemporary academic literature and international reports produced by leading educational organizations. Special attention is given to the impact of digital platforms, multimedia learning tools, and interactive educational technologies on students’ motivation and participation. The article also discusses the challenges associated with digital education, including technological inequalities, digital literacy gaps, and pedagogical adaptation. The study concludes that digital learning resources, when used strategically and pedagogically, can significantly enhance student engagement and contribute to more effective educational processes in universities.
subject: Articles
  topic: section
subject: digital education, higher education, student engagement, digital learning resources, online learning
  topic: keywords
creator: Madona Kebadze
creator: Lia Baindurashvili
creator: Nino Chankotadze
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-17
publication date: 2026-03-17
starting page: 76
ending page: 82

ARSMEDICA: AN ARTIFICIAL INTELLIGENCE–DRIVEN PLATFORM FOR SCHOLARLY DATABASE NAVIGATION AND SCIENTIFIC PUBLISHING SUPPORT
type: item
description: The rapid growth of scientific information has considerably complicated the process of identifying reliable scholarly databases, appropriate academic journals, and relevant scientific events. Researchers, particularly students and early-career scientists, often encounter difficulties when attempting to locate trustworthy publishing platforms and establish communication with editorial offices. As a result, the dissemination of scientific research may become inefficient and time-consuming.
subject: Articles
  topic: section
subject:
  topic: keywords
  value: artificial intelligence, scholarly databases, academic publishing, research, platforms, scientific communication, digital research infrastructure, Ai-assisted academic writing, research information systems.
creator: Arziqulov Fazliddin
creator: Amirqulov Raxmatulla
creator: Amirqulova Sugdiyona
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-17
publication date: 2026-03-17
starting page: 65
ending page: 75

BODY MASS INDEX–ASSOCIATED PATTERNS OF REPRODUCTIVE DYSFUNCTION IN PUBERTAL GIRLS
type: item
description: Reproductive dysfunction in pubertal girls remains one of the most relevant problems in pediatric gynecology and endocrinology, as it develops during the critical period of maturation of the hypothalamic-pituitary-ovarian axis and may substantially influence future reproductive potential. Menstrual disorders associated with abnormalities in body mass index (BMI) are of particular importance, since both obesity and underweight can significantly affect the tempo of pubertal development, the establishment of ovulatory function, hormonal homeostasis, and the morphofunctional characteristics of the reproductive organs. During puberty, alterations in metabolic status often become one of the key factors contributing to the development of amenorrhea, opsomenorrhea, acyclic uterine bleeding, and other menstrual disturbances. Therefore, the study of clinical, hormonal, and instrumental features of reproductive dysfunction in adolescent girls according to BMI is of clear scientific and practical relevance.
subject: Articles
  topic: section
creator: T. M. Kamalov
creator: D. A. Musakhodjaeva
creator: Z. Sh. Azizova
creator: S.A. Muzafarova
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-15
publication date: 2026-03-15
starting page: 60
ending page: 64

NANOBIOPHYSICAL CHARACTERIZATION OF TARGETED DRUG DELIVERY SYSTEMS FOR ENHANCED CANCER THERAPY EFFICIENCY
type: item
description: Targeted drug delivery systems represent a major advancement in modern oncological treatment strategies. Nanobiophysics provides a quantitative framework for understanding nanoparticle–cell interactions, membrane transport mechanisms, and controlled therapeutic release dynamics. The present study evaluates the biophysical properties of engineered nanoparticles designed for targeted cancer therapy and analyzes their efficiency through computational modeling and experimental parameter simulation.
subject: Articles
  topic: section
subject: Nanobiophysics; Targeted drug delivery; Cancer therapy; Nanoparticles; Controlled release kinetics; Cellular uptake; Diffusion modeling; Biomedical nanotechnology
  topic: keywords
creator: Fazliddin Arzikulov
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-14
publication date: 2026-03-14
starting page: 41
ending page: 59

THE INFLUENCE OF LIFESTYLE AND METABOLIC SYNDROME ON BREAST CANCER INCIDENCE AND PROGNOSIS
type: item
description: Breast cancer incidence continues to rise globally, partly due to lifestyle transitions and increasing prevalence of metabolic disorders. Metabolic syndrome—a cluster of conditions including central obesity, insulin resistance, dyslipidemia, and hypertension—has been increasingly recognized as a significant contributor to breast cancer development and progression. Lifestyle factors such as sedentary behavior, high-calorie diets, excessive body weight, and reduced physical activity influence hormonal balance, chronic inflammation, and metabolic dysregulation, thereby promoting carcinogenesis.
subject: Articles
  topic: section
subject: Breast cancer; lifestyle factors; metabolic syndrome; obesity; insulin resistance; inflammation; prognosis; prevention; public health; cancer epidemiology.
  topic: keywords
creator: Dallo Salva Faekovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-09
publication date: 2026-03-09
starting page: 27
ending page: 40

THE ROLE OF GENETIC SCREENING AND BRCA TESTING IN EARLY IDENTIFICATION OF HIGH-RISK BREAST CANCER PATIENTS
type: item
description: Breast cancer is a multifactorial disease influenced by both environmental and genetic determinants. Among hereditary factors, mutations in the BRCA1 and BRCA2 genes represent the most significant genetic predisposition associated with increased lifetime risk of breast and ovarian cancers. Women carrying pathogenic BRCA mutations face a substantially higher probability of developing early-onset and biologically aggressive breast cancer compared to the general population. Therefore, early identification of high-risk individuals through genetic screening has become a critical component of modern oncology. Genetic screening and BRCA testing enable risk stratification, personalized surveillance strategies, and implementation of preventive interventions, including intensified imaging follow-up, chemoprevention, and prophylactic surgery. Advances in molecular diagnostics, including next-generation sequencing, have improved accessibility and accuracy of mutation detection. Early identification of mutation carriers not only benefits individual patients but also allows cascade testing among family members, contributing to broader preventive impact. In transitional healthcare systems, however, the integration of genetic screening into routine clinical practice remains limited due to restricted access to molecular testing, high costs, and insufficient awareness among both healthcare providers and the population. Expanding genetic counseling services and incorporating risk-based screening protocols may significantly improve early detection rates and reduce mortality among genetically predisposed women. This article analyzes the clinical significance of BRCA mutations, evaluates the role of genetic screening in early risk identification, and discusses practical considerations for implementing genetic testing programs within emerging healthcare environments.
subject: Articles
  topic: section
subject: Breast cancer; genetic screening; BRCA1; BRCA2; hereditary breast cancer; high-risk patients; genetic counseling; early detection; precision medicine; oncology prevention.
  topic: keywords
creator: Dallo Salva Faekovna
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-09
publication date: 2026-03-09
starting page: 13
ending page: 26

PEDAGOGICAL CONDITIONS FOR DEVELOPING STUDENTS’ COMPARATIVE THINKING THROUGH FABLES
type: item
description: Pedagogical conditions for the formation of comparative thinking in students through parables are an area that requires special attention and in-depth analysis as one of the urgent issues in today's education system. As is known, the experience of the education system of developed countries shows that not only knowledge itself, but also the ability to think deeply, to compare each fact and phenomenon with other facts and phenomena, to have an independent opinion, to analyze and generalize them according to certain criteria are among the main competencies for a modern person. Therefore, in pedagogical activity, especially at the higher education stage, it is important to develop comparative thinking skills at a high level in order to form students not only with scientific knowledge, but also as specialists with developed multi-competent, analytical and creative thinking.
subject: Articles
  topic: section
subject:
  topic: keywords
  value: Parables, comparative thinking, pedagogical conditions, thinking in students, educational environment, interactive methods, analytical competence, modern educational process, critical thinking, independent analysis.
creator: Khasanova Volida Erkin qizi
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-09
publication date: 2026-03-09
starting page: 5
ending page: 12

CLINICAL AND PATHOPHYSIOLOGICAL FEATURES OF THE DEVELOPMENT OF ISCHEMIC HEART DISEASE IN PATIENTS WITH DIABETES MELLITUS
type: item
description: Diabetes mellitus is one of the most pressing problems of modern medicine and represents a significant risk factor for the development of cardiovascular diseases. According to the World Health Organization, patients with diabetes mellitus have a significantly higher risk of developing cardiovascular diseases, particularly ischemic heart disease, which is one of the leading causes of disability and mortality worldwide.
subject: Articles
  topic: section
subject: diabetes mellitus, including chronic hyperglycemia, lipid metabolism disorders, oxidative stress
  topic: keywords
creator: Mo‘minjonov X.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-08
publication date: 2026-03-08
starting page: 1
ending page: 4

TUMOR-RELATED CEREBRAL EDEMA: MECHANISMS AND IMAGING FEATURES
type: item
description: Brain and central nervous system (CNS) malignancies constitute a serious global health concern due to their high mortality rates, significant socioeconomic burden, limited survival outcomes, and profound negative impact on patients’ quality of life. In 2020, approximately 308,102 new cases of brain and CNS tumors were diagnosed worldwide, representing nearly 1.6% of all newly identified cancers. In the same year, an estimated 251,329 deaths were attributed to these tumors, ranking them among the major causes of cancer-related mortality. Although survival rates vary depending on geographic location and access to advanced medical care, the overall prognosis remains unfavorable because many of these tumors are highly aggressive and often detected at advanced stages. Neuroimaging plays a pivotal role in the diagnosis, therapeutic planning, and postoperative monitoring of brain tumors. Computed tomography (CT) remains one of the fundamental imaging modalities in clinical practice. Both contrast-enhanced and non-contrast CT scans are widely used for noninvasive tumor characterization, evaluation of tumor size and location, assessment of mass effect, and pre-treatment planning. CT imaging is also essential in differentiating neoplastic lesions from other intracranial conditions.
subject: Articles
  topic: section
creator: Khoshimov I. G.
creator: Yakubov N. I.,
creator: Madumarova Z. Sh
creator: Zulunov A. T.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-04
publication date: 2026-03-04
starting page: 62
ending page: 66

TALABALARDA SUN’IY INTELLEKT ASOSIDA OGʻZAKI NUTQNI RIVOJLANTIRISHNING MASHQLAR TIZIMI
type: item
description: Mazkur maqolada talabalarda sun’iy intellekt (SI) texnologiyalari asosida og‘zaki nutqni rivojlantirishga qaratilgan mashqlar tizimi ishlab chiqiladi va tahlil qilinadi. SI asosidagi nutqni aniqlash (speech recognition), chatbotlar, virtual suhbatdoshlar va adaptiv platformalarning didaktik imkoniyatlari ko‘rib chiqiladi. Og‘zaki nutqni shakllantirishning bosqichma-bosqich mashqlar tizimi taklif etilib, uning psixologik-pedagogik va lingvodidaktik asoslari yoritiladi. Tadqiqot natijasida talabalarning nutqiy faolligini oshirish, fonetik aniqlikni yaxshilash va kommunikativ kompetensiyani rivojlantirish bo‘yicha metodik tavsiyalar ishlab chiqilgan.
subject: Articles
  topic: section
subject: sun’iy intellekt, og‘zaki nutq, nutqni rivojlantirish, speech recognition, chatbot, kommunikativ kompetensiya, lingvodidaktika, interaktiv mashqlar.
  topic: keywords
creator: Jo‘rabekova Madina Jumanazar qizi
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-03-03
publication date: 2026-03-03
starting page: 57
ending page: 61

ЭМБРИОН РИВОЖЛАНИШДАГИ КЕЛИБ ЧИҚАДИГАН НУҚСОНЛАР
type: item
description: Эмбрион ривожланиши инсон ҳаётининг энг муҳим босқичларидан бири ҳисобланади. Шу даврда ҳомиланинг барча аъзолари ва тизимлари шаклланади. Агар ушбу жараёнда турли ички ёки ташқи омиллар таъсир кўрсатса, эмбрион ривожланишида нуқсонлар келиб чиқиши мумкин. Бу нуқсонлар туғма касалликлар сифатида намоён бўлиб, боланинг соғлиғи ва ҳаётига жиддий таъсир кўрсатади.
subject: Articles
  topic: section
creator: Нуриддинова Муниса Тоҳир қизи
creator: Илмий раҳбар: Мухамеджанова Нодира
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-02-25
publication date: 2026-02-25
starting page: 54
ending page: 56

STUDYING THE TENDENCY OF PATIENTS WITH CHRONIC HEART-VASCULAR AND RESPIRATORY DISEASES LIVING IN THE VILLAGE TO BE TREATED
type: item
description: The article examines the inclination of the rural population to treat cardiovascular and respiratory diseases using the example of the Samarkand region. This indicator was assessed using the widely used Morisky-Green questionnaire in the world. It is indicated that patients have a low propensity for treatment, one of the reasons for which is non-compliance with indications, as well as insufficient communication between the doctor and the patient. Successful management of chronic diseases requires not only effective medical procedures but also the active participation of patients in the treatment process. The main factor determining the effectiveness of treatment for non-communicable chronic diseases is predisposition to treatment. Therefore, it is advisable to accelerate the integration of modern technologies into practical medicine.
subject: Articles
  topic: section
subject: Cardiovascular diseases, healthcare system, arterial hypertension, ischemic heart disease, chronic heart failure, bronchial asthma, chronic obstructive pulmonary disease, propensity for treatment.
  topic: keywords
creator: Khusinova Sh. A.
creator: Turaqulov R. I.
creator: Gadaeva N. A.
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-02-18
publication date: 2026-02-18
starting page: 50
ending page: 53

PRACTICE OF ATTRACTING GRANTS, FUNDS AND INTERNATIONAL FINANCIAL RESOURCES IN HIGHER EDUCATION
type: item
description: Higher education institutions today operate in a complex and competitive global environment, where securing sufficient financial resources is crucial for sustaining academic excellence, research, and innovation. Traditional funding sources, such as government allocations and tuition fees, are often insufficient to cover the increasing costs of infrastructure, faculty development, scientific research, and student services. Consequently, the practice of attracting grants, funds, and international financial resources has become an essential strategy for universities aiming to ensure financial stability and enhance their global competitiveness.
subject: Articles
  topic: section
creator: Rakhmatullaev Jamshid Murodillaevich
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-02-15
publication date: 2026-02-15
starting page: 46
ending page: 49

DIGITALIZING HIGHER EDUCATION HEMIS INFORMATION SYSTEM
type: item
description: Reforms underway in Uzbekistan’s higher education system are closely linked to the “Digital Uzbekistan – 2030” strategy, and in this process the higher education management information system—HEMIS—is taking shape as a central infrastructure. With HEMIS, it becomes possible to plan the educational process, monitor students’ academic performance, account for faculty workload, and manage contracts and financial operations in a digital environment. This thesis analyzes HEMIS’s functional role in digitalizing higher education, its place within the mobile application and an integrated digital ecosystem, as well as challenges related to technical infrastructure, digital competencies, and information security, and directions for addressing them. The impact of digital transformation on education quality, management efficiency, and transparency is briefly summarized based on existing research and regulatory documents.
subject: Articles
  topic: section
subject: Digitalizing higher education, HEMIS, management information system, digital ecosystem, digital transformation, HEMIS Mobile.
  topic: keywords
creator: Ergashev Muhammadsodiq Uchqun o‘g‘li
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-02-15
publication date: 2026-02-15
starting page: 41
ending page: 45

METHODOLOGY OF USING VISUAL TOOLS IN TEACHING GEOMETRY TOPICS
type: item
description: Amid declining international mathematics scores, this paper proposes a methodological framework for integrating visual tools into geometry education to enhance student comprehension and engagement. Geometry, with its inherently visual nature, provides a fertile ground for leveraging technology to foster critical cognitive skills. This extended abstract outlines a structured approach that utilizes a range of visual aids, from Dynamic Geometry Software (DGS) like GeoGebra to immersive technologies such as Augmented and Virtual Reality (AR/VR). The methodology is grounded in established pedagogical models, including TPACK and SAMR, to ensure a meaningful integration of technology. It details a six-stage lesson plan (motivation, exploration, conjecture, explanation/proof, practice, reflection) designed to address common student errors and promote deeper conceptual understanding. The framework also incorporates assessment strategies, including rubrics and e-portfolios, to measure the development of spatial reasoning and problem-solving competencies. This research aims to provide educators with a practical, evidence-based methodology to transform traditional geometry instruction into a dynamic, interactive, and effective learning experience.
subject: Articles
  topic: section
subject: Geometry Education, Visual Tools, TPACK, Dynamic Geometry Software, Spatial Reasoning, Augmented Reality, Assessment Rubrics.
  topic: keywords
creator: Elmurodov Jamshid Asatillayevich
creator: Axmadov Samandar Zoir o‘g‘li
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-02-15
publication date: 2026-02-15
starting page: 32
ending page: 40

EARLY DIAGNOSIS AND PROGNOSTIC OPTIMIZATION OF ACUTE KIDNEY INJURY IN THE INTENSIVE CARE SETTING
type: item
description: Acute kidney injury (AKI) remains a pressing clinical problem in intensive care units worldwide due to its high incidence and significant impact on patient morbidity and mortality. Despite advances in critical care, AKI continues to pose diagnostic and therapeutic challenges, particularly in its early stages when intervention can most effectively improve outcomes.
subject: Articles
  topic: section
creator: Po‘latov Ma’rufjon Davlatbek o‘g‘li
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-02-12
publication date: 2026-02-12
starting page: 28
ending page: 31

BIOLOGICAL DIVERSITY IN THE HYDROSPHERE SHELL AND ITS SIGNIFICANCE IN NATURE
type: item
description: This article discusses the hydrosphere, one of the earth's crusts, and its importance on the earth's surface, the level of biodiversity, the role of water resources in the development of organisms, and concepts related to natural sciences, ecology, in particular, biodiversity. In addition, information about the world's oceans and seas, the diversity of various organisms adapted to different conditions, the relationship between biomasses, the higher biomass of aquatic organisms than terrestrial organisms, the beauties of nature, the importance of the hydrosphere in educating young people to love nature and protect natural resources, are also discussed.
subject: Articles
  topic: section
subject: ocean, sea, plant, animal, biodiversity, algae.
  topic: keywords
creator: Oripov Shoxrux Ilxom o‘g‘li
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-02-11
publication date: 2026-02-11
starting page: 24
ending page: 27

ЛОГИСТИКА ХИЗМАТЛАРИДА СТРАТЕГИК РЕЖАЛАШТИРИШНИНГ МОҲИЯТИ ВА АҲАМИЯТИ
type: item
description: Мазкур мақолада логистика хизматларида стратегик режалаштиришнинг моҳияти, унинг назарий асослари ва амалий аҳамияти тадқиқ этилган. Тадқиқот давомида стратегик режалаштириш логистика тизимининг самарадорлигини ошириш, харажатларни оптималлаштириш ва рақобатбардошликни таъминлашда муҳим омил эканлиги асослаб берилган. Шунингдек, замонавий логистика хизматларида қўлланилаётган стратегик ёндашувлар таҳлил қилинган.
subject: Articles
  topic: section
subject: логистика хизматлари, стратегик режалаштириш, таъминот занжири, рақобатбардошлик, самарадорлик.
  topic: keywords
creator: Абдухаликова Комила Абдухаликовна
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-02-11
publication date: 2026-02-11
starting page: 18
ending page: 23

САВДО ХИЗМАТЛАРИ ТИЗИМИДА МАҲСУЛОТЛАР СИФАТИНИ РИВОЖЛАНТИРИШ ЙЎЛЛАРИ
type: item
description: Ушбу мақолада савдо хизматлари тизимида маҳсулотлар сифатини ривожлантириш ва юқори даражага кўтаришнинг замонавий услубларини жорий этиш лозимлигига алоҳида эътибор қаратилган.
subject: Articles
  topic: section
subject: сифат, тизим, маҳсулот, хизмат, рақобатбардошлик, мижоз, мулоқот.
  topic: keywords
creator: Абдухолиқова Фарангиз Абдухолиқ қизи
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0
date: 2026-02-11
publication date: 2026-02-11
starting page: 12
ending page: 17